Model‐Informed Dose Selection for Xentuzumab, a Dual Insulin‐Like Growth Factor‐I/II—Neutralizing Antibody-Reference-Cited by-同舟云学术

Model‐Informed Dose Selection for Xentuzumab, a Dual Insulin‐Like Growth Factor‐I/II—Neutralizing Antibody

Published:2019-11-19 Issue:3 Volume:107 Page:597-606
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Parra‐Guillen Zinnia P.¹²,Schmid Ulrike³,Janda Alvaro¹²,Freiwald Matthias³,Troconiz Iñaki F.¹²

Affiliation:

1. Pharmacometrics & Systems Pharmacology Research Unit Department of Pharmaceutical Technology and Chemistry School of Pharmacy and Nutrition University of Navarra Pamplona Spain

2. Navarra Institute for Health Research IdiSNA Pamplona Spain

3. Translational Medicine and Clinical Pharmacology Boehringer Ingelheim Pharma GmbH & Co. KG Biberach an der Riß Germany

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1648

Reference25 articles.

1. Insulin and insulin-like growth factor signalling in neoplasia

2. IGF-1 Receptor Inhibitors in Clinical Trials—Early Lessons

3. Molecular interactions of the IGF system

4. Control of cell survival by IGF signaling pathways

5. The IGF-I Signaling Pathway

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