A phase 1 trial of xentuzumab, an IGF‐neutralizing antibody, in Japanese patients with advanced solid tumors
Author:
Affiliation:
1. Department of Experimental Therapeutics National Cancer Center Hospital East Kashiwa Japan
2. Nippon Boehringer Ingelheim Co., Ltd Kobe Japan
3. EPS Corporation Tokyo Japan
4. Nippon Boehringer Ingelheim Co., Ltd. Tokyo Japan
Funder
Boehringer Ingelheim
Publisher
Wiley
Subject
Cancer Research,Oncology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.15231
Reference20 articles.
1. The insulin and insulin‐like growth factor receptor family in neoplasia: an update;Pollak M;Nat Rev Cancer,2012
2. A randomized phase II/III study of dalotuzumab in combination with cetuximab and irinotecan in chemorefractory, KRAS wild‐type, metastatic colorectal cancer;Sclafani F;J Natl Cancer Inst,2015
3. Randomized, phase III trial of figitumumab in combination with erlotinib versus erlotinib alone in patients with nonadenocarcinoma nonsmall‐cell lung cancer;Scagliotti GV;Ann Oncol,2015
4. Insulin‐like growth factor (IGF) pathway targeting in cancer: role of the IGF axis and opportunities for future combination studies;Simpson A;Target Oncol,2017
5. Pharmacodynamic and antineoplastic activity of BI 836845, a fully human IGF ligand‐neutralizing antibody, and mechanistic rationale for combination with rapamycin;Friedbichler K;Mol Cancer Ther,2014
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1. Emerging Role of IGF-1 in Prostate Cancer: A Promising Biomarker and Therapeutic Target;Cancers;2023-02-17
2. Obesity and endocrine-related cancer: The important role of IGF-1;Frontiers in Endocrinology;2023-01-23
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