Discovery of Novel Biased Opioid Receptor Ligands through Structure‐Based Pharmacophore Virtual Screening and Experiment-Reference-Cited by-同舟云学术

Discovery of Novel Biased Opioid Receptor Ligands through Structure‐Based Pharmacophore Virtual Screening and Experiment

Published:2019-09-26 Issue:20 Volume:14 Page:1783-1794
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Jeong Pyeonghwa¹,Kim Soo‐Kyung²,Li Quanjie²³⁴,Oh Su‐jin⁵,Son Seonil⁵,Chen Guangju³,Tan Hongwei³,Kim Siwon⁶⁷,Park Jong‐Hyun⁶,Park Ki Duk⁶⁷⁸,Kim Yeo Ok⁹,Yoon Myung Ha⁹,Kim Yong‐Chul¹⁵^ORCID,Goddard William A.²^ORCID

Affiliation:

1. Department of Biomedical Science and EngineeringGwangju Institute of Science and Technology 123 Cheomdan-gwagiro Buk-gu 61005 South Korea

2. Materials and Process Simulation Center (MC-139-74)California Institute of Technology Pasadena California 91125 USA

3. College of ChemistryBeijing Normal University Beijing 100875 P. R. China

4. Institute of Medicinal BiotechnologyChinese Academy of Medical Science Beijing 100050 P. R. China

5. School of Life SciencesGwangju Institute of Science and Technology 123 Cheomdan-gwagiro Buk-gu 61005 South Korea

6. Convergence Research Center for Diagnosis, Treatment, and Care system of DementiaKorea Institute of Science and Technology (KIST) Seoul 02792 South Korea

7. Division of Bio-Medical Science and TechnologyKIST SchoolKorea University of Science and Technology Seoul 02792 South Korea

8. KHU–KIST Department of Converging Science and TechnologyKyung Hee University Seoul 02447 South Korea

9. Department of Anesthesiology and Pain MedicineMedical SchoolChonnam National University Gwangju 501-757 South Korea

Funder

Gwangju Institute of Science and Technology

National Research Foundation of Korea

China Scholarship Council

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900418

Reference40 articles.

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3. Quality of life and cancer pain: satisfaction and side effects with transdermal fentanyl versus oral morphine.

4. Center for Substance Abuse Treatment Medication-Assisted Treatment for Opioid Addiction in Opioid Treatment Program Treatment Improvement Protocol (TIP) Series 43 HHS Publication No. (SMA) 12-4214. Rockville MD: Substance Abuse and Mental Health Services Administration 2005.

5. Opioid-Induced Constipation: Challenges and Therapeutic Opportunities

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