4“‐O‐Alkylated α‐Galactosylceramide Analogues as i NKT‐Cell Antigens: Synthetic, Biological, and Structural Studies-Reference-Cited by-同舟云学术

4“‐O‐Alkylated α‐Galactosylceramide Analogues as i NKT‐Cell Antigens: Synthetic, Biological, and Structural Studies

Published:2018-12-17 Issue:1 Volume:14 Page:147-168
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Janssens Jonas¹²^ORCID,Bitra Aruna³,Wang Jing³,Decruy Tine⁴⁵,Venken Koen⁴⁵,van der Eycken Johan²,Elewaut Dirk⁴⁵,Zajonc Dirk M.³⁴,van Calenbergh Serge¹^ORCID

Affiliation:

1. Laboratory for Medicinal Chemistry Department of Pharmaceutics (FFW) Ghent University Ottergemsesteenweg 460 9000 Ghent Belgium

2. Laboratory for Organic and Bioorganic Synthesis Department of Organic and Macromolecular Chemistry Ghent University Krijgslaan 281 (S4) 9000 Ghent Belgium

3. Division of Immune Regulation La Jolla Institute for Allergy and Immunology (LJI) 9420 Athena Circle La Jolla CA 92037 USA

4. Department of Internal Medicine Faculty of Medicine and Health Sciences Ghent University De Pintelaan 185 9000 Ghent Belgium

5. VIB Inflammation Research Center UGent-VIB Research Building FSVM Technologiepark 927 9052 Zwijnaarde (Ghent) Belgium

Funder

National Institute of Health

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201800649

Reference40 articles.

1. Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus

2. Structure-Activity Relationship of .alpha.-Galactosylceramides against B16-Bearing Mice

3. Structural determination of lipid antigens captured at the CD1d–T-cell receptor interface

4. CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides

5. The crystal structure of human CD1d with and without α-galactosylceramide

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