Modified 5′-Trityl Nucleosides as Inhibitors ofPlasmodium falciparumdUTPase-Reference-Cited by-同舟云学术

Modified 5′-Trityl Nucleosides as Inhibitors ofPlasmodium falciparumdUTPase

Published:2011-01-18 Issue:2 Volume:6 Page:309-320
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Ruda Gian Filippo,Nguyen Corinne,Ziemkowski Przemysław,Felczak Krzysztof,Kasinathan Ganasan,Musso-Buendia Alexander,Sund Christian,Zhou Xiao Xiong,Kaiser Marcel,Ruiz-Pérez Luis M.,Brun Reto,Kulikowski Tadeusz,Johansson Nils Gunnar,González-Pacanowska Dolores,Gilbert Ian H.

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201000445/fullpdf

Reference30 articles.

1. Health topics: http://www.who.int/topics/malaria/en/

2. dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae.

3. Lethality of a dut (deoxyuridine triphosphatase) mutation in Escherichia coli

4. dUTPase as a Platform for Antimalarial Drug Design: Structural Basis for the Selectivity of a Class of Nucleoside Inhibitors

5. Deoxyuridine Triphosphate Nucleotidohydrolase as a Potential Antiparasitic Drug Target

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