Medicinal chemistry aspects of uracil containing dUTPase inhibitors targeting colorectal cancer

Author:

Backer Nabeel,Kumar Adarsh,Singh Ankit Kumar,Singh Harshwardhan,Narasimhan Balasubramanian,Kumar PradeepORCID

Funder

University of Central Punjab

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference69 articles.

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3. Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-XL in addition to Bax and p53 status;Violette;Acc Chem Res,2002

4. dUTPase: the frequently overlooked enzyme encoded by many retroviruses;Hizi;Retrovirology,2015

5. dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer;Ladner;Cancer Res,2000

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