Structure-Based Design of Microsomal Prostaglandin E2Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme-Reference-Cited by-同舟云学术

Structure-Based Design of Microsomal Prostaglandin E2Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme

Published:2016-02-24 Issue:6 Volume:11 Page:612-619
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Lauro Gianluigi¹,Tortorella Paolo²,Bertamino Alessia¹,Ostacolo Carmine³,Koeberle Andreas⁴,Fischer Katrin⁴,Bruno Ines¹,Terracciano Stefania¹,Gomez-Monterrey Isabel Maria³,Tauro Marilena²,Loiodice Fulvio²,Novellino Ettore³,Riccio Raffaele¹,Werz Oliver⁴,Campiglia Pietro¹,Bifulco Giuseppe¹

Affiliation:

1. Department of Pharmacy; Università di Salerno; Via Giovanni Paolo II 132 84084 Fisciano, SA Italy

2. Department of Pharmacy; Università degli Studi di Bari “Aldo Moro”; Via Orabona 4 70126 Bari Italy

3. Department of Pharmacy; Università degli Studi di Napoli “Federico II”; Via Montesano 49 80131 Napoli Italy

4. Department of Pharmaceutical/Medicinal Chemistry; Institute of Pharmacy; University of Jena; Philosophenweg 14 07743 Jena Germany

Funder

University of Salerno (Italy)

Associazione Italiana Ricerca sul Cancro (AIRC)

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference70 articles.

1. Inflammation and cancer

2. Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms

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