Structure–Affinity Relationships of Fluorinated Spirocyclic σ 2 Receptor Ligands with an Exocyclic Benzylamino Moiety-Reference-Cited by-同舟云学术

Structure–Affinity Relationships of Fluorinated Spirocyclic σ 2 Receptor Ligands with an Exocyclic Benzylamino Moiety

Published:2019-07-12 Issue:15 Volume:14 Page:1392-1402
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Bergkemper Melanie¹,Kronenberg Elisabeth¹,Schepmann Dirk¹,Ludwig Friedrich‐Alexander²,Brust Peter²,Wünsch Bernhard¹³^ORCID

Affiliation:

1. Institut für Pharmazeutische und Medizinische ChemieWestfälische Universität Münster Corrensstraße 48 48149 Münster Germany

2. Institut für Radiopharmazeutische Krebsforschung, Forschungsstelle LeipzigHelmholtz-Zentrum Dresden-Rossendorf Permoserstr. 15 04318 Leipzig Germany

3. Cells-in-Motion Cluster of Excellence (EXC 1003-CiM)Westfälische Wilhelms-Universität 48149 Münster Germany

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900284

Reference26 articles.

1. Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

2. Crystal structure of the human σ1 receptor

3. Identification of the gene that codes for the σ2 receptor

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