Structure-Activity Studies ofN-Butyl-1-deoxynojirimycin (NB-DNJ) Analogues: Discovery of Potent and Selective Aminocyclopentitol Inhibitors of GBA1 and GBA2

Author:

Gu Xingxian12ORCID,Gupta Vijayalaxmi3ORCID,Yang Yan4ORCID,Zhu Jin-Yi4ORCID,Carlson Erick J.2ORCID,Kingsley Carolyn2ORCID,Tash Joseph S.3ORCID,Schönbrunn Ernst4ORCID,Hawkinson Jon2ORCID,Georg Gunda I.2ORCID

Affiliation:

1. Department of Medicinal Chemistry; University of Kansas; Lawrence KS 66045 USA

2. Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development; University of Minnesota; Minneapolis MN 55414 USA

3. University of Kansas Medical Center; Kansas City KS 66160 USA

4. H. Lee Moffitt Cancer Center & Research Institute; Tampa FL 33612 USA

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

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