A Focus on Unusual ECL2 Interactions Yields β 2 ‐Adrenergic Receptor Antagonists with Unprecedented Scaffolds-Reference-Cited by-同舟云学术

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A Focus on Unusual ECL2 Interactions Yields β 2 ‐Adrenergic Receptor Antagonists with Unprecedented Scaffolds

Published:2020-04-17 Issue:10 Volume:15 Page:882-890
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Scharf Magdalena M.¹^ORCID,Zimmermann Mirjam²,Wilhelm Florian²³,Stroe Raimond²⁴,Waldhoer Maria²,Kolb Peter¹^ORCID

Affiliation:

1. Department of Pharmaceutical ChemistryPhilipps-University Marburg Marbacher Weg 6 35037 Marburg Germany

2. InterAx BiotechPARK innovAARE 5234 Villigen Switzerland

3. Department of Biosystems Science and Engineering ETHETH Zürich Mattenstrasse 26 4058 Basel Switzerland

4. Department of Drug Design and PharmacologyUniversity of Copenhagen Universitetsparken 2 2100 Copenhagen Denmark

Funder

Københavns Universitet

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900715

Reference36 articles.

1. The Significance of G Protein-Coupled Receptor Crystallography for Drug Discovery

2. Three Generations of β-blockers: History, Class Differences and Clinical Applicability

3. Efficacy of infantile hepatic hemangioma with propranolol treatment

4. Central Nervous System Effects of Oral Propranolol for Infantile Hemangioma: A Systematic Review and Meta-Analysis

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