Structural Characterization and Computer-Aided Optimization of a Small-Molecule Inhibitor of the Arp2/3 Complex, a Key Regulator of the Actin Cytoskeleton-Reference-Cited by-同舟云学术

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Structural Characterization and Computer-Aided Optimization of a Small-Molecule Inhibitor of the Arp2/3 Complex, a Key Regulator of the Actin Cytoskeleton

Published:2012-05-23 Issue:7 Volume:7 Page:1286-1294
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Baggett Andrew W.,Cournia Zoe,Han Min Suk,Patargias George,Glass Adam C.,Liu Shih-Yuan,Nolen Brad J.

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201200104/fullpdf

Reference49 articles.

1. Actin, a Central Player in Cell Shape and Movement

2. Kinetic evidence for a monomer activation step in actin polymerization

3. New mechanisms and functions of actin nucleation

4. The ARP2/3 complex: an actin nucleator comes of age

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1. CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes;EMBO Reports;2024-07-15

2. CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes;2023-11-26

3. Herpes Simplex Virus Type 1 Infection Induces the Formation of Tunneling Nanotubes;Microorganisms;2023-07-28

4. The Impact of Arp2/3 Complex Inhibition on Cytoskeleton Dynamics and Mitochondrial Function during Goat Oocyte Meiosis;Animals;2023-01-12

5. Increased cross-presentation by dendritic cells and enhanced anti-tumour therapy using the Arp2/3 inhibitor CK666;British Journal of Cancer;2023-01-11

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