1. Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 1‐1‐1, Tsushima‐Naka, Okayama 700‐8530 (Japan), Fax: (+81) 86‐251‐7926
2. Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 562 Nanatsuka, Shobara,Hiroshima 727‐0023 (Japan)