Discovery of 6‐Arylurea‐2‐arylbenzoxazole and 6‐Arylurea‐2‐arylbenzimidazole Derivatives as Angiogenesis Inhibitors: Design, Synthesis and in vitro Biological Evaluation-Reference-Cited by-同舟云学术

Discovery of 6‐Arylurea‐2‐arylbenzoxazole and 6‐Arylurea‐2‐arylbenzimidazole Derivatives as Angiogenesis Inhibitors: Design, Synthesis and in vitro Biological Evaluation

Published:2019-06-18 Issue:13 Volume:14 Page:1291-1302
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Zi Mengli¹,Liu Feifei²,Wu Di¹,Li Ke³,Zhang Da¹,Zhu Changcheng⁴,Zhang Zhiyun⁵,Li Linghua⁵,Zhang Conghai¹,Xie Mingjin¹,Lin Jun¹,Zhang Jihong²,Jin Yi¹^ORCID

Affiliation:

1. Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education and Yunnan Province, School of Chemical Science and TechnologyYunnan University Kunming 650091 P.R. China

2. Laboratory of Molecular Genetics of Aging and TumorsMedical SchoolKunming University of Science and Technology Kunming 650500 P.R. China

3. Biomedical DepartmentYunnan Cancer Hospital, Third Affiliated Hospital of Kunming Medical University Kunming 650118 P.R. China

4. Institute of Drug Research and DevelopmentKunming Pharmaceutical Corporation Kunming 650100 P.R. China

5. Department of AnorectalKunming Municipal Hospital of Traditional Chinese Medicine Kunming 650011 P.R. China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900216

Reference75 articles.

1. Concept, mechanisms and therapeutics of angiogenesis in cancer and other diseases

2. Angiogenesis in cancer and other diseases

3. Vascular-specific growth factors and blood vessel formation

4. Regulating the angiogenic balance in tissues: A potential role for the proliferative state of fibroblasts

5. Antiangiogenic Agents: an Update on Small Molecule VEGFR Inhibitors

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Efficient synthesis of novel 1,10 phenanthroline-substituted imidazolium salts: Exploring their anticancer applications;European Journal of Medicinal Chemistry;2024-11

2. In silico insights into design of novel VEGFR-2 inhibitors: SMILES-based QSAR modelling, and docking studies on substituted benzo-fused heteronuclear derivatives;SAR and QSAR in Environmental Research;2024-04-02

3. Research and development ofN,N′-diarylureas as anti-tumor agents;RSC Medicinal Chemistry;2023

4. Chemistry of Biologically Active Benzimidazole Scaffolds: Medicinal Chemistry Perspective;Mini-Reviews in Organic Chemistry;2022-11

5. Imidazole-based phenanthroline derivatives induce DNA damage-mediated apoptosis to suppress hepatocellular carcinoma;Journal of Holistic Integrative Pharmacy;2022-06