Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase-Reference-Cited by-同舟云学术

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase

Published:2017-11-27 Issue:1 Volume:13 Page:48-66
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Asquith Christopher R. M.¹^ORCID,Laitinen Tuomo²,Bennett James M.³,Godoi Paulo H.⁴,East Michael P.⁵,Tizzard Graham J.⁶,Graves Lee M.⁵,Johnson Gary L.⁵,Dornsife Ronna E.¹,Wells Carrow I.¹^ORCID,Elkins Jonathan M.³⁴^ORCID,Willson Timothy M.¹^ORCID,Zuercher William J.¹^ORCID

Affiliation:

1. Structural Genomics Consortium, UNC Eshelman School of Pharmacy; University of North Carolina at Chapel Hill; Chapel Hill NC 27599 USA

2. School of Pharmacy, Faculty of Health Sciences; University of Eastern Finland; 70211 Kuopio Finland

3. Structural Genomics Consortium and Target Discovery Institute, Nuffield Department of Clinical Medicine; University of Oxford; Old Road Campus Research Building Oxford OX3 7DQ UK

4. Structural Genomics Consortium; Universidade Estadual de Campinas-UNICAMP; Campinas São Paulo 13083-886 Brazil

5. Department of Pharmacology; University of North Carolina at Chapel Hill; NC 27599 USA

6. UK National Crystallography Service, School of Chemistry; University of Southampton; Highfield Campus Southampton SO17 1BJ UK

Funder

Wellcome Trust

National Institutes of Health

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201700663/fullpdf

Reference66 articles.

1. Role of Cyclin G-associated Kinase in Uncoating Clathrin-coated Vesicles from Non-neuronal Cells

2. GAK: a cyclin G associated kinase contains a tensin/auxilin-like domain 1

3. Structure, Expression, and Chromosomal Localization of Human GAK

4. CK2 and GAK/auxilin2 Are Major Protein Kinases in Clathrin-Coated Vesicles

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