Discovery of a Novel Scaffold as an Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Based on the Pyrrolopiperazinone Alkaloid, Longamide B-Reference-Cited by-同舟云学术

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Discovery of a Novel Scaffold as an Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Based on the Pyrrolopiperazinone Alkaloid, Longamide B

Published:2016-12-05 Issue:24 Volume:11 Page:2682-2689
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Shiokawa Zenyu¹²,Kashiwabara Emi¹,Yoshidome Daisuke³,Fukase Koichi²,Inuki Shinsuke¹,Fujimoto Yukari¹

Affiliation:

1. Department of Chemistry; Faculty of Science and Technology; Keio University; 3-14-1 Hiyoshi, Kohoku-ku Yokohama Kanagawa 223-8522 Japan

2. Department of Chemistry; Graduate School of Science; Osaka University; 1-1 Machikaneyama-cho Toyonaka-shi Osaka 560-0043 Japan

3. Schrödinger K.K.; 17F Marunouchi Trust Tower North 1-8-1 Marunouchi Chiyoda-ku Tokyo 100-0005 Japan

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference36 articles.

1. Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated l-tryptophan metabolism

2. Ido expression by dendritic cells: tolerance and tryptophan catabolism

3. IDO: more than an enzyme

4. The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pyrrole: An Essential Framework in the Development of Therapeutic Agents and Insightful Analysis of Structure‐Active Relationships;ChemistrySelect;2024-08-16

2. Synthesis and Application of Immunomodulatory Natural Products;Journal of Synthetic Organic Chemistry, Japan;2023-09-01

3. Syntheses and Preliminary Biological Evaluations of the Dibromopyrrole‐Containing Marine Natural Products Agesasine A, Agesasine B, Longamide E and Various Congeners;European Journal of Organic Chemistry;2023-04-04

4. Accessing Chiral Pyrrolodiketopiperazines under Organocatalytic Conditions;Organic Letters;2022-12-29

5. Indoleamine 2, 3-dioxygenase 1 inhibitory compounds from natural sources;Frontiers in Pharmacology;2022-11-04

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