Designing Irreversible Inhibitors-Worth the Effort?-Reference-Cited by-同舟云学术

Designing Irreversible Inhibitors-Worth the Effort?

Published:2015-11-23 Issue:1 Volume:11 Page:22-30
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

González-Bello Concepción¹^ORCID

Affiliation:

1. Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS); Universidade de Santiago de Compostela; calle Jenaro de la Fuente s/n Santiago de Compostela 15782 Spain

Funder

Spanish Ministry of Economy and Competitiveness

Xunta de Galicia

European Regional Development Fund (ERDF)

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference74 articles.

1. The resurgence of covalent drugs

2. Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies

3. Drug discovery for a new generation of covalent drugs

4. COVALENT DRUGS FORM LONG-LIVED TIES

5. Strategies for discovering and derisking covalent, irreversible enzyme inhibitors

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