Solubility-Improved 10-O -Substituted SN-38 Derivatives with Antitumor Activity

Author:

Doi Hisashi1,Kida Tatsuya1,Nishino Kosuke1,Nakatsuji Masatoshi2,Sakamoto Shiho2,Shimizu Shota2,Teraoka Yoshiaki2,Tamura Yasuhisa3,Kataoka Yosky3,Inui Takashi2

Affiliation:

1. Labeling Chemistry Team, Division of Bio-Function Dynamics Imaging; RIKEN Center for Life Science Technologies, CLST; 6-7-3 Minatojima, minamimachi, Chuo-ku Kobe Hyogo 650-0047 Japan

2. Graduate School of Life and Environmental Science; Osaka Prefecture University; 1-1 Gakuen-cho, Naka-ku Sakai Osaka 599-8531 Japan

3. Cellular Function Imaging Team, Division of Bio-function Dynamics Imaging; RIKEN Center for Life Science Technologies, CLST; 6-7-3, Minatojima minamimachi, Chuo-ku Kobe Hyogo 650-0047 Japan

Funder

Individual Knowledge Research in FY 2012 Strategic Program for R&D (President's Fund) from RIKEN

a Grant-in-Aid for Scientific Research (A) from JSPS

the Foundation for Promotion of Cancer Research in Japan

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

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