LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients-Reference-Cited by-同舟云学术

LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Published:2019-01-10 Issue:2 Volume:247 Page:228-240
ISSN:0022-3417
Container-title:The Journal of Pathology
language:en
Short-container-title:J. Pathol.

Author:

Xie Yuan¹,Sundström Anders¹,Maturi Naga P¹,Tan E-Jean¹^ORCID,Marinescu Voichita D¹²,Jarvius Malin³,Tirfing Malin¹,Jin Chuan¹,Chen Lei¹,Essand Magnus¹,Swartling Fredrik J¹,Nelander Sven¹,Jiang Yiwen¹⁴,Uhrbom Lene¹^ORCID

Affiliation:

1. Department of Immunology, Genetics and Pathology; Uppsala University and Science for Life Laboratory, Rudbeck Laboratory; Uppsala Sweden

2. Department of Medical Biochemistry and Microbiology, Biomedical Centre; Uppsala University and Science for Life Laboratory; Uppsala Sweden

3. Department of Medical Sciences, Cancer Pharmacology and Computational Medicine; Uppsala University and Science for Life Laboratory; Uppsala Sweden

4. Department of Medical Biochemistry and Biophysics, Division of Molecular Neurobiology; Karolinska Institutet; Stockholm Sweden

Funder

Cancerfonden

Vetenskapsrådet

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/path.5186/fullpdf

Reference41 articles.

1. CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in the United States in 2010-2014;Ostrom;Neuro Oncol,2017

2. Cancer stem cells in glioblastoma;Lathia;Genes Dev,2015

3. Identification of a cancer stem cell in human brain tumors;Singh;Cancer Res,2003

4. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens;Pollard;Cell Stem Cell,2009

5. The somatic genomic landscape of glioblastoma;Brennan;Cell,2013

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