Synthesis of a Phosphonate-Linked Aminoglycoside-Coenzyme A Bisubstrate and Use in Mechanistic Studies of an Enzyme Involved in Aminoglycoside Resistance-Reference-Cited by-同舟云学术

Synthesis of a Phosphonate-Linked Aminoglycoside-Coenzyme A Bisubstrate and Use in Mechanistic Studies of an Enzyme Involved in Aminoglycoside Resistance

Published:2009-02-16 Issue:9 Volume:15 Page:2064-2070
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Gao Feng,Yan Xuxu,Auclair Karine

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference37 articles.

1. Regio- and Chemoselective 6′-N-Derivatization of Aminoglycosides: Bisubstrate Inhibitors as Probes To Study Aminoglycoside 6′-N-Acetyltransferases

2. Angew. Chem. Int. Ed. 2005, 44, 6859-6862.

3. Synthesis and use of sulfonamide-, sulfoxide-, or sulfone-containing aminoglycoside–CoA bisubstrates as mechanistic probes for aminoglycoside N-6′-acetyltransferase

4. Kinetic and Structural Analysis of Bisubstrate Inhibition of the Salmonella enterica Aminoglycoside 6‘-N-Acetyltransferase,

5. Kinetic Mechanism of the GCN5-Related Chromosomal Aminoglycoside Acetyltransferase AAC(6‘)-Ii from Enterococcus faecium: Evidence of Dimer Subunit Cooperativity

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