The Development of a Fluorescence‐Based Competitive Assay Enabled the Discovery of Dimeric Cyclic Peptide Modulators of Ubiquitin Chains
Author:
Affiliation:
1. Schulich Faculty of Chemistry Technion-Israel Institute of Technology Haifa 3200008 Israel
2. Department of Chemistry School of Science The University of Tokyo Tokyo 113-0033 Japan
Funder
European Research Council
Publisher
Wiley
Subject
General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202013392
Reference28 articles.
1. A comprehensive map of molecular drug targets
2. Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges
3. Methods for generating and screening libraries of genetically encoded cyclic peptides in drug discovery
4. A RaPID way to discover nonstandard macrocyclic peptide modulators of drug targets
5. Macrocycles as protein–protein interaction inhibitors
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1. Combining Chemical Protein Synthesis and Random Nonstandard Peptides Integrated Discovery for Modulating Biological Processes;Accounts of Chemical Research;2023-06-13
2. Highly Efficient Cyclization Approach of Propargylated Peptides via Gold(I)-Mediated Sequential C–N, C–O, and C–C Bond Formation;ACS Central Science;2021-11-18
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