Methods for generating and screening libraries of genetically encoded cyclic peptides in drug discovery
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/s41570-019-0159-2.pdf
Reference104 articles.
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2. Marsault, E. & Peterson, M. L. Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery. J. Med. Chem. 54, 1961–2004 (2011).
3. Tavassoli, A. SICLOPPS cyclic peptide libraries in drug discovery. Curr. Opin. Chem. Biol. 38, 30–35 (2017).
4. Freidinger, R. M., Veber, D. F., Perlow, D. S., Brooks, J. R. & Saperstein, R. Bioactive conformation of luteinizing hormone-releasing hormone: evidence from a conformationally constrained analog. Science 210, 656–658 (1980).
5. Veber, D. F. et al. Nonreducible cyclic analogues of somatostatin. J. Am. Chem. Soc. 98, 2367–2369 (1976).
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