Affiliation:
1. State Key Laboratory of Chem/Bio-Sensing and Chemometrics Advanced Catalytic Engineering Research Center of the Ministry of Education College of Chemistry and Chemical Engineering, the National Supercomputer Centers in Changsha Hunan University Changsha 410082 China
2. Shenzhen Institute of Hunan University Shenzhen 518057 China
3. School of Chemistry and Chemical Engineering Jishou University Jishou 416000 China
Abstract
AbstractAlanine is widely employed for synthesizing polymers, pharmaceuticals, and agrochemicals. Electrocatalytic coupling of biomass molecules and waste nitrate is attractive for the nitrate removal and alanine production under ambient conditions. However, the reaction efficiency is relatively low due to the activation of the stable substrates, and the coupling of two reactive intermediates remains challenging. Herein, we realize the integrated tandem electrochemical‐chemical‐electochemical synthesis of alanine from the biomass‐derived pyruvic acid (PA) and waste nitrate (NO3−) catalyzed by PdCu nano‐bead‐wires (PdCu NBWs). The overall reaction pathway is demonstrated as a multiple‐step catalytic cascade process via coupling the reactive intermediates NH2OH and PA on the catalyst surface. Interestingly, in this integrated tandem electrochemical‐chemical‐electrochemical catalytic cascade process, Cu facilitates the electrochemical reduction of nitrate to NH2OH intermediates, which chemically couple with PA to form the pyruvic oxime, and Pd promotes the electrochemical reduction of pyruvic oxime to the desirable alanine. This work provides a green strategy to convert waste NO3− to wealth and enriches the substrate scope of renewable biomass feedstocks to produce high‐value amino acids.