Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants

Author:

Li Aitao1ORCID,Acevedo‐Rocha Carlos G.2ORCID,D'Amore Lorenzo3ORCID,Chen Jinfeng4,Peng Yaqin1,Garcia‐Borràs Marc3ORCID,Gao Chenghua1,Zhu Jinmei1,Rickerby Harry5,Osuna Sílvia36ORCID,Zhou Jiahai4ORCID,Reetz Manfred T.78ORCID

Affiliation:

1. School of life science Hubei University State Key Laboratory of Biocatalysis and Enzyme Engineering #368 Youyi Road Wuhan 430062 P.R. China

2. Biosyntia ApS 2100 Copenhagen Denmark

3. Institut de Química Computacional i Catàlisi and Departament de Química Universitat de Girona Carrer Maria Aurèlia Capmany 69 17003 Girona Catalonia Spain

4. State Key Laboratory of Bio-organic and Natural Products Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Shanghai 200032 P. R. China

5. LabGenius G.01-06 Cocoa Studios 100 Drummond Rd London SE16 4DG UK

6. ICREA Pg. Lluís Companys 23 08010 Barcelona Spain

7. Max-Planck-Institut für Kohlenforschung Kaiser-Wilhelm-Platz 1 45470 Muelheim Germany

8. Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences 32 West 7th Avenue Tianjin 300308 P. R. China

Publisher

Wiley

Subject

General Medicine

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