An Unusual Oxidative Rearrangement Catalyzed by a Divergent Member of the 2‐Oxoglutarate‐Dependent Dioxygenase Superfamily during Biosynthesis of Dehydrofosmidomycin-Reference-Cited by-同舟云学术

An Unusual Oxidative Rearrangement Catalyzed by a Divergent Member of the 2‐Oxoglutarate‐Dependent Dioxygenase Superfamily during Biosynthesis of Dehydrofosmidomycin

Published:2022-06-07 Issue:30 Volume:134 Page:
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angewandte Chemie

Author:

Parkinson Elizabeth I.¹²³^ORCID,Lakkis Hani G.²,Alwali Amir A.²,Metcalf Mary Elizabeth M.¹⁴,Modi Ramya²^ORCID,Metcalf William W.¹⁴^ORCID

Affiliation:

1. Institute for Genomic Biology University of Illinois at Urbana-Champaign 1206 W. Gregory Dr. Urbana IL 61801 USA

2. Department of Chemistry Purdue University Herbert C. Brown Laboratory of Chemistry, Room 4103E 560 Oval Drive, Box 59 West Lafayette IN 47907 USA

3. Department of Medicinal Chemistry and Molecular Pharmacology Purdue University Herbert C. Brown Laboratory of Chemistry, Room 4103E 560 Oval Drive, Box 59 West Lafayette IN 47907 USA

4. Department of Microbiology University of Illinois at Urbana-Champaign, B103C&LSL 601 S. Goodwin Urbana IL 61801 USA

Funder

National Institute of General Medical Sciences

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202206173

Reference48 articles.

1. Diversity and abundance of phosphonate biosynthetic genes in nature

2. Biosynthesis of Phosphonic and Phosphinic Acid Natural Products

3. Phosphonate biosynthesis and catabolism: a treasure trove of unusual enzymology

4. Evidence that the Fosfomycin-Producing Epoxidase, HppE, Is a Non–Heme-Iron Peroxidase

5. An unusual carbon–carbon bond cleavage reaction during phosphinothricin biosynthesis

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