A Modular Access to 1,2‐ and 1,3‐Disubstituted Cyclobutylboronic Esters by Consecutive Radical Additions
Author:
Affiliation:
1. Laboratoire de Synthèse Organique CNRS UMR 7652 Ecole polytechnique 91128 Palaiseau Cedex France
2. Laboratoire de Chimie Moleculaire CNRS UMR 9168 Ecole polytechnique 91128 Palaiseau Cedex France
Funder
Fondation de l'École Polytechnique
Publisher
Wiley
Subject
General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202113333
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4. Discovery of Two Clinical Histamine H3 Receptor Antagonists: trans-N-Ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and trans-3-Fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]-N-(2-methylpropyl)cyclobutanecarboxamide (PF-03654764)
5. Synthesis and in vivo evaluation of bicyclic gababutins
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