Determination and structural characterization of ravidasvir metabolites by LC coupled to triple quadrupole linear ion trap MS: Application to pharmacokinetics and phase I metabolism in rats

Author:

Kaddah Mohamed Mohamed Yousri1ORCID,Talaat Wael2ORCID,El Demellawy Maha A.3

Affiliation:

1. Pharmaceutical and Fermentation Industries Development Center City of Scientific Research and Technological Applications New Borg El‐Arab Alexandria Egypt

2. Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy Damanhour University Damanhour Egypt

3. Center of Excellence for Preclinical Research in Drug Development City of Scientific Research and Technological Applications New Borg El‐Arab Alexandria Egypt

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference33 articles.

1. Reduction of carry‐over in column‐switching HPLC/MS system with automated system washing procedure for highly sensitive direct analysis of donepezil in dog plasma;Asakawa Y.;Journal of Pharmaceutical and Biomedical Analysis,2007

2. A stability‐indicating QTRAP LC‐MS/MS method for identification and structural characterization of degradation products of indapamide;Attia K. A. M.;Analytical Methods,2016

3. Excellent outcome of direct antiviral treatment for chronic hepatitis C in Switzerland;Bachofner J.;Swiss Medical Weekly,2018

4. Beyond pass/fail: A procedure for evaluating the effect of carryover in bioanalytical LC/MS/MS methods;Clouser‐Roche A.;Journal of Pharmaceutical and Biomedical Analysis,2008

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