A Population Pharmacokinetic Model of Vonoprazan: Evaluating the Effects of Race, Disease Status, and Other Covariates on Exposure-Reference-Cited by-同舟云学术

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A Population Pharmacokinetic Model of Vonoprazan: Evaluating the Effects of Race, Disease Status, and Other Covariates on Exposure

Published:2022-02-08 Issue: Volume: Page:
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharma

Author:

Scarpignato Carmelo¹,Leifke Eckhard²,Smith Neila²,Mulford Darcy J.²,Lahu Gezim³,Facius Axel³,Howden Colin W.⁴

Affiliation:

1. Department of Health Sciences United Campus of Malta Msida MSD Malta

2. Phathom Pharmaceuticals Research and Development Chicago Illinois USA

3. thinkQ² AG Baar Switzerland

4. Division of Gastroenterology University of Tennessee Health Science Center Memphis Tennessee USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.2019

Reference36 articles.

1. Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK-438 (vonoprazan), a novel potassium-competitive acid blocker, in healthy male subjects

2. Acid-inhibitory effects of vonoprazan 20 mg compared with esomeprazole 20 mg or rabeprazole 10 mg in healthy adult male subjects - a randomised open-label cross-over study

3. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Rising TAK-438 (Vonoprazan) Doses in Healthy Male Japanese/non-Japanese Subjects

4. Review article: potassium‐competitive acid blockers for the treatment of acid‐related disorders

5. Acid Suppressant Therapy: a Step Forward with Potassium-Competitive Acid Blockers

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1. Population pharmacokinetic analysis of zastaprazan (JP‐1366), a novel potassium‐competitive acid blocker, in patients and healthy volunteers;CPT: Pharmacometrics & Systems Pharmacology;2024-09-13

2. Safety of potassium-competitive acid blockers in the treatment of gastroesophageal reflux disease;Expert Opinion on Drug Metabolism & Toxicology;2024-08-27

3. Potassium-competitive Acid Blockers: Current Clinical Use and Future Developments;Current Gastroenterology Reports;2024-08-15

4. A Comprehensive Review on the Efficacy and Safety of Vonoprazan in the Management of Gastric Acid-Related Diseases;Cureus;2024-07-17

5. Generation of realistic virtual adult populations using a model-based copula approach;Journal of Pharmacokinetics and Pharmacodynamics;2024-06-06

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