Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK-438 (vonoprazan), a novel potassium-competitive acid blocker, in healthy male subjects-Reference-Cited by-同舟云学术

Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK-438 (vonoprazan), a novel potassium-competitive acid blocker, in healthy male subjects

Published:2015-02-23 Issue:7 Volume:41 Page:636-648
ISSN:0269-2813
Container-title:Alimentary Pharmacology & Therapeutics
language:en
Short-container-title:Aliment Pharmacol Ther

Author:

Jenkins H.¹,Sakurai Y.²,Nishimura A.²,Okamoto H.²,Hibberd M.¹,Jenkins R.¹,Yoneyama T.³,Ashida K.⁴,Ogama Y.⁵,Warrington S.⁶

Affiliation:

1. Takeda Development Centre Europe Ltd; London UK

2. Takeda Pharmaceutical Company Ltd; Osaka Japan

3. Takeda Pharmaceutical Company Ltd; Fujisawa; Japan

4. Department of Gastroenterology and Hepatology; Saiseikai Nakatsu Hospital; Osaka Japan

5. Medical Co. LTA Honjo Clinic (current Sumida Hospital); Tokyo Japan

6. Hammersmith Medicines Research; London UK

Funder

Takeda Development Centre Europe Ltd.

Takeda Pharmaceutical Company Ltd.

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/apt.13121/fullpdf

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4. The gastric H, K ATPase as a drug target: past, present, and future;Sachs;J Clin Gastroenterol,2007

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