Potential Clinical Uses of CDK Inhibitors: Lessons from Synthetic Lethality Screens-Reference-Cited by-同舟云学术

Potential Clinical Uses of CDK Inhibitors: Lessons from Synthetic Lethality Screens

Published:2015-06-25 Issue:6 Volume:35 Page:1156-1174
ISSN:0198-6325
Container-title:Medicinal Research Reviews
language:en
Short-container-title:Med. Res. Rev.

Author:

Vymětalová Ladislava¹,Kryštof Vladimír¹

Affiliation:

1. Laboratory of Growth Regulators; Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University and Institute of Experimental Botany AS CR; Šlechtitelů 11 CZ-78371 Olomouc Czech Republic

Funder

Czech Science Foundation

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/med.21354/fullpdf

Reference102 articles.

1. The determination and interpretation of the therapeutic index in drug development;Muller;Nat Rev Drug Discov,2012

2. The concept of synthetic lethality in the context of anticancer therapy;Kaelin;Nat Rev Cancer,2005

3. Identification of the molecular basis of doxorubicin-induced cardiotoxicity;Zhang;Nat Med,2012

4. Central nervous system toxicity of high-dose systemic cytosine arabinoside;Lazarus;Cancer,1981

5. Clinical, radiologic, and histopathologic studies on pulmonary toxicity induced by treatment with bleomycin (NSC-125066);Lena;Cancer Chemother Rep,1972

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of quinazoline derivatives as a novel class of potent and in vivo efficacious LSD1 inhibitors by drug repurposing;European Journal of Medicinal Chemistry;2021-12

2. Clinical Candidates Targeting the ATR–CHK1–WEE1 Axis in Cancer;Cancers;2021-02-14

3. miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer;Cancer Gene Therapy;2020-09-18

4. [1,2,3]Triazolo[4,5-d]pyrimidine derivatives incorporating (thio)urea moiety as a novel scaffold for LSD1 inhibitors;European Journal of Medicinal Chemistry;2020-02

5. Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma;Molecular Medicine Reports;2019-11-20