Maduramicin induces cardiac muscle cell death by the ROS‐dependent PTEN/Akt–Erk1/2 signaling pathway

Author:

Chen Xin123,Li Yue1,Feng Meng1,Hu Xiaoyu1,Zhang Hai1,Zhang Ruijie1,Dong Xiaoqing1,Liu Chunxiao1,Zhang Zhao1,Jiang Shanxiang3,Huang Shile24ORCID,Chen Long1ORCID

Affiliation:

1. Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University Nanjing China

2. Department of Biochemistry and Molecular Biology Louisiana State University Health Sciences Center Shreveport Louisiana

3. Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University Nanjing China

4. Feist‐Weiller Cancer Center, Louisiana State University Health Sciences Center Shreveport Louisiana

Funder

National Natural Science Foundation of China

Foundation for the National Institutes of Health

American Cancer Society

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference39 articles.

1. Cardiomyopathy of ruminants induced by the litter of poultry fed on rations containing the ionophore antibiotic, maduramicin. II. Macropathology and histopathology;Bastianello S. S.;Onderstepoort Journal of Veterinary Research,1995

2. Focus on PTEN regulation

3. MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

4. N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain

5. Maduramicin Inhibits Proliferation and Induces Apoptosis in Myoblast Cells

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