Dynamic mechanistic modeling of the multienzymatic one-pot reduction of dehydrocholic acid to 12-keto ursodeoxycholic acid with competing substrates and cofactors-Reference-Cited by-同舟云学术

Dynamic mechanistic modeling of the multienzymatic one-pot reduction of dehydrocholic acid to 12-keto ursodeoxycholic acid with competing substrates and cofactors

Published:2015-02-02 Issue:2 Volume:31 Page:375-386
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnol Progress

Author:

Sun Boqiao¹,Hartl Florian¹,Castiglione Kathrin¹,Weuster-Botz Dirk¹

Affiliation:

1. Inst. of Biochemical Engineering, Dept. of Mechanical Engineering; Technische Universität München; Garching 85748 Germany

Funder

Federal Ministry of Education and Research, Germany

Publisher

Wiley

Subject

Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.2036/fullpdf

Reference33 articles.

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2. Final outcome of ursodeoxycholic acid treatment in 126 patients with radiolucent gallstones;Gleeson;Q J Med.,1990

3. Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double-blind trial;Leuschner;Gastroenterology,1989

4. Novel whole-cell biocatalysts with recombinant hydroxysteroid dehydrogenases for the asymmetric reduction of dehydrocholic acid;Braun;Appl Microbiol Biotechnol.,2012

5. Enzymatic synthesis of 12-ketoursodeoxycholic acid from dehydrocholic acid in a membrane reactor;Carrea;Biotechnol Lett.,1992

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