Multicentre prospective cohort study of body mass index and postoperative complications following gastrointestinal surgery
Author:
, Drake T M1, Nepogodiev D1, Chapman S J1, Glasbey J C1, Khatri C1, Kong C Y1, Claireaux H A1, Bath M F1, Mohan M1, McNamee L1, Kelly M1, Mitchell H1, Fitzgerald J E1, Harrison E M1, Bhangu A1, Claireaux H A2, Antoniou I3, Dean R4, Davies N5, Trecarten S6, Henderson I6, Holmes C7, Wylie J8, Shuttleworth R H8, Jindal A9, Hughes F10, Gouda P10, McNamee L11, Fleck R12, Hanrahan M13, Karunakaran P14, Chen J H15, Sykes M C15, Sethi R K16, Suresh S16, Patel P17, Patel M17, Varma R K18, Mushtaq J18, Gundogan B19, Bolton W20, Mohan M21, Khan T21, Burke J22, Morley R22, Favero N23, Adams R24, Thirumal V25, Kennedy E D26, Ong K K27, Tan Y H27, Gabriel J28, Bakhsh A29, Low J Y L29, Yener A30, Paraoan V31, Preece R32, Tilston T W32, Cumber E33, Dean S34, Ross T35, McCance E35, Amin H36, Satterthwaite L37, Clement K D38, Gratton R38, Mills E D38, Chiu S M38, Hung G38, Rafiq N M38, Hayes J D B38, Robertson K L38, Dynes K38, Huang H C39, Assadullah S39, Duncumb J W39, Moon R D C39, Poo S X39, Mehta J K39, Joshi K R39, Callan R39, Norris J M39, Chilvers N J39, Keevil H39, Jull P39, Mallick S40, Elf D40, Carr L40, Player C41, Barton E C41, Martin A L41, Ratu S G41, Roberts E J41, Phan P N41, Dyal A R41, Rogers J E41, Henson A D41, Reid N B42, Burke D42, Culleton G42, Lynne S42, Burke D42, Mansoor S43, Brennan C43, Blessed R43, Holloway C43, Hill A43, Goldsmith T43, Mackin S43, Kim S44, Woin E44, Brent G44, Coffin J44, Ziff O44, Momoh Z45, Debenham R45, Ahmed M45, Yong C S46, Wan J C46, Copley H C46, Raut P46, Chaudhry F I46, Shuttleworth R H47, Nixon G47, Dorman C47, Tan R47, Kanabar S47, Canning N47, Dolaghan M47, Bell N47, McMenamin M47, Chhabra A48, Duke K48, Turner L48, Patel T48, Chew L S48, Mirza M48, Lunawat S48, Oremule B48, Ward N49, Khan M49, Tan E T50, Maclennan D50, McGregor R J50, Chisholm E G50, Griffin E J50, Bell L50, Hughes B A51, Davies J51, Haq H51, Ahmed H51, Ungcharoen N51, Whacha C51, Thethi R51, Markham R M52, Lee A H Y52, Batt E52, Bullock N P52, Francescon C T52, Davies J E52, Shafiq N M52, Zhao J53, Vivekanantham S53, Barai I53, Allen J L Y53, Marshall D C53, McIntyre C J53, Wilson H C P53, Ashton A J53, Lek C53, Behar N54, Davis-Hall M54, Seneviratne N54, Kim S54, Esteve L54, Sirakaya M54, Ali S54, Pope S54, Ahn J S54, Craig-McQuaide A54, Gatfield W A55, Leong S55, Demetri A M55, Kerr A L55, Rees C56, Loveday J56, Liu S56, Wijesekera M56, Maru D56, Attalla M56, Smith N56, Brown D57, Sritharan P57, Shah A57, Charavanamuttu V57, Heppenstall-Harris G57, Ng K57, Raghvani T57, Rajan N57, Hulley K57, Moody N58, Williams M58, Cotton A58, Sharifpour M59, Lwin K N59, Bright M59, Chitnis A R59, Abdelhadi M59, Semana A D59, Morgan F60, Reid R60, Dickson J60, Anderson L60, McMullan R60, Dickson J60, Ahern N60, Asmadi A60, Anderson L B60, Lua Boon Xuan J61, Crozier L61, McAleer S61, Lees D M62, Adebayo A A62, Das M62, Amphlett A H62, Al-Robeye A63, Valli A63, Khangura J63, Winarski A63, Ali A63, Khangura J63, Woodward H64, Gouldthrope C64, Turner M64, Sasapu K64, Tonkins M65, Wild J R L65, Robinson M65, Hardie J65, Heminway R65, Narramore R65, Ramjeeawon N65, Hibberd A65, Winslow F66, Ho W66, Chong B F66, Lim K66, Ho S66, Crewdson J A67, Singagireson S67, Kalra N67, Koumpa F67, Jhala H67, Soon W C67, Karia M67, Rasiah M G67, Xylas D67, Gilbert H68, Sundar-Singh M68, Wills J68, Mushtaq J69, Akhtar S69, Patel S69, Hu L69, Brathwaite-Shirley C69, Nayee H69, Amin O69, Rangan T69, Turner E J H69, McCrann C70, Shepherd R70, Patel N70, Prest-Smith J70, Auyoung E70, Murtaza A70, Coates A70, Prys-Jones O71, King M71, Gaffney S71, Dewdney C J71, Nehikhare I71, Lavery J71, Bassett J72, Davies K72, Ahmad K72, Collins A72, Acres M72, Egerton C72, Khan T72, Cheng K73, Chen X73, Chan N73, Sheldon A73, Khan S73, Empey J73, Ingram E73, Malik A73, Johnstone M73, Goodier R74, Shah J P74, Giles J E74, Sanders J A74, McLure S W74, Pal S74, Rangedara A74, Baker A N74, Asbjoernsen C A74, Girling C75, Gray L75, Gauntlett L75, Joyner C75, Qureshi S75, Dean S75, Mogan Y P76, Ng J C K76, Kumar A N76, Park J H76, Tan D76, Choo K P76, Raman K P76, Buakuma P76, Xiao C76, Govinden S76, Thompson O D77, Charalambos M A77, Brown E77, Karsan R B77, Dogra T77, Bullman L M77, Dawson P M77, Frank A L78, Abid H78, Tung L78, Qureshi U78, Tahmina A78, Matthews B W78, Harris R T79, O'Connor A79, Mazan K79, Iqbal S79, Stanger S A79, Thompson J D79, Sullivan J A L80, Uppal E80, MacAskill A80, Bamgbose F A80, Neophytou C80, Carroll A F80, Rookes C W80, Datta U80, Dhutia A J80, Rashid S81, Ahmed N81, Lo T81, Bhanderi S82, Blore C D82, Ahmed S82, Shaheen H82, Abburu S82, Majid S82, Abbas Z82, Talukdar S S82, Ahmed S82, Burney L J83, Patel J B83, Al-Obaedi O83, Roberts A W83, Al-Obaedi O83, Mahboob S83, Singh B84, Sheth S84, Karia P84, Prabhudesai A84, Kow K84, Koysombat K84, Wang S84, Morrison P84, Maheswaran Y84, Keane P84, Copley P C85, Brewster O85, Xu G X85, Harries P85, Wall C85, Al-Mousawi A86, Bonsu S86, Cunha P86, Ward T86, Paul J86, Nadanakumaran K86, Tayeh S86, Ward T86, Holyoak H86, Remedios J86, Theodoropoulou K86, Ward T86, Luhishi A87, Jacob L87, Long F87, Atayi A87, Sarwar S87, Parker O87, Harvey J88, Ross H88, Rampal R88, Thomas G88, Vanmali P88, McGowan C88, Stein J88, Robertson V89, Carthew L89, Teng V89, Fong J89, Street A N90, Thakker C E90, O'Reilly D91, Bravo M91, Pizzolato A91, Khokhar H A91, Ryan M91, Cheskes L91, Carr R91, Salih A E91, Bassiony S92, Yuen R92, Chrastek D92, Rosen O'Sullivan H92, Amajuoyi A92, Wang A92, Sitta O92, Wye J92, Qamar M A93, Major C93, Kaushal A93, Morgan C94, Petrarca M94, Allot R94, Verma K94, Dutt S94, Allot R94, Chilima C P94, Peroos S94, Allot R94, Kosasih S R95, Chin H95, Ashken L95, Pearse R J95, O'Loughlin R A95, Menon A95, Singh K95, Norton J95, Sagar R96, Jathanna N96, Rothwell L96, Watson N96, Harding F96, Dube P96, Khalid H97, Punjabi N97, Sagmeister M97, Gill P97, Shahid S97, Hudson-Phillips S97, George D97, Ashwood J97, Lewis T97, Dhar M98, Sangal P98, Rhema I A98, Kotecha D98, Dean R98, Afzal Z98, Syeed J A98, Prakash E98, Jalota P98, Dean R98, Herron J99, Kimani L99, Delport A99, Shukla A99, Agarwal V100, Parthiban S100, Thakur H100, Cymes W100, Rinkoff S100, Turnbull J A101, Hayat M101, Darr S101, Khan U101, Lim J101, Higgins A101, Lakshmipathy G102, Forte B102, Canning E102, Jaitley A102, Lamont J102, Toner E102, Ghaffar A102, McDowell M102, Salmon D102, Gouda P103, O'Carroll O103, Khan A103, Kelly M E103, Clesham K103, Palmer C103, Lyons R103, Kelly M E103, Bell A103, Chin R103, Waldron R M103, Kelly M E103, Trimble A104, Cox S E104, Ashfaq U104, Campbell J104, Holliday R B S104, McCabe G104, Morris F105, Priestland R105, Dean S105, Vernon O K105, Ledsam A105, Vaughan R105, Lim D106, Bakewell Z R106, Hughes R K106, Koshy R M107, Jackson H R107, Narayan P107, Cardwell A E107, Jubainville C L107, Arif T107, Elliott L E107, Gupta V107, Arif T107, Bhaskaran G108, Singh K108, Odeleye A108, Ahmed F108, Shah R108, Odeleye A108, Pickard J108, Suleman Y N108, Odeleye A108, North A S109, McClymont L F109, Hussain N109, Ibrahim I109, Ng G S109, Wong V109, Lim A E109, Harris L N109, Tharmachandirar T109, Mittapalli D109, Patel V110, Lakhani M110, Davies N111, Bazeer H Z111, Narwani V111, Sandhu K K111, Wingfield L R111, Gentry S111, Adjei H111, Bhatti M111, Braganza L111, Barnes J112, Mistry S112, Chillarge G112, Stokes S112, Cleere J112, Wadanamby S112, Bucko A M112, Meek J112, Boxall N112, Heywood E G112, Wiltshire J J112, Toh C112, Ward A E112, Shurovi B N112, Drake T M112, Horth D113, Patel B Y113, Ali B113, Spencer T113, Axelson T113, Kretzmer L113, Chhina C113, Anandarajah C114, Fautz T114, Horst C114, Thevathasan A A115, Ng J Q115, Hirst F115, Brewer C F116, Logan A E116, Lockey J W116, Forrest P R116, Keelty N116, Wood A D116, Springford L R116, Avery P116, Schulz T M116, Bemand T P116, Howells L116, Collier H117, Khajuria A117, Tharakan R G117, Parsons S117, Buchan A M118, McGalliard R J118, Mason J D118, Cundy O J118, Li N118, Redgrave N A118, Watson R P118, Pezas T P118, Dennis Y F118, Segall E118, Hameed M118, Lynch A S118, Chamberlain M119, Peck F S119, Neo Y N119, Russell G119, Elseedawy M119, Lee S119, Foster N L119, Soo Y H119, Puan L119, Dennis R120, Goradia H120, Qureshi A120, Osman S121, Reeves T121, Dinsmore L121, Marsden M121, Lu Q121, Pitts-Tucker T121, Dunn C E122, Walford R A122, Heathcote E122, Martin R122, Pericleous A122, Brzyska K122, Reid K G122, Williams M R122, Wetherall N122, McAleer E123, Thomas D123, Kiff R123, Gouldthrope C123, Milne S124, Holmes M J V124, Stokes S124, Bartlett J124, Carvalho J L ucas124, Bloomfield T124, Tongo F125, Bremner R H125, Yong N125, Atraszkiewicz B A125, Mehdi A125, Tahir M125, Sherliker G X J125, Tear A K125, Pandey A125, Broyd A126, Omer H M126, Raphael M126, Chaudhry W W126, Shahidi S126, Jawad A S126, Gill C K126, Hindle Fisher I126, Adeleja I126, Clark I J126, Aidoo-Micah G E126, Stather P W127, Salam G J127, Glover T E127, Deas G127, Sim N K127, Obute R D127, Wynell-Mayow W M127, Sait M S128, Mitha N128, Bernier G L128, Siddiqui M128, Shaunak R128, Wali A128, Cuthbert G128, Bhudia R129, Webb E129, Shah S129, Ansari N129, Perera M129, Kelly N129, McAllister R130, Stanley G H130, Keane C P130, Shatkar V130, Maxwell-Armstrong C130, Henderson L A131, Maple N131, Manson R131, Adams R D131, Brown E131, Semple E131, Mills M132, Daoub A132, Marsh A132, Ramnarine A132, Hartley J132, Malaj M132, Jewell P D133, Whatling E A133, Hitchen N133, Chen M133, Goh B134, Fern J134, Rogers S134, Derbyshire L134, Robertson D T135, Abuhussein N135, Deekonda P135, Abid A135, Bakhsh A135, Harrison P L M136, Aildasani L136, Turley H136, Sherif M A137, Pandey G137, Filby J J137, Johnston A137, Burke E137, Mohamud M137, Gohil K137, Tsui A Y137, Singh R137, Lim S J138, O'Sullivan K138, McKelvey L L138, O'Neill S138, Roberts H F138, Brown F S138, Cao Y138, Buckle R T138, Liew Y138, Sii S138, Ventre C M138, Graham C J138, Filipescu T138, Yousif A139, Dawar R139, Wright A139, Peters M139, Varley R139, Owczarek S139, Hartley S139, Khattak M140, Iqbal A140, Ali M140, Durrani B140, Narang Y140, Bethell G S140, Horne L140, Pinto R140, Nicholls K141, Kisyov I141, Torrance H D141, Patel P141, Patel M141, English W141, Lakhani S M141, Ashraf S F141, Venn M141, Elangovan V142, Kazmi Z142, Brecher J142, Sukumar S142, Mastan A142, Mortimer A142, Parker J142, Boyle J142, Elkawafi M143, Beckett J143, Mohite A143, Narain A143, Mazumdar E143, Sreh A143, Hague A143, Weinberg D143, Fletcher L143, Steel M144, Shufflebotham H144, Masood M144, Sinha Y144, Amin H144, Jenvey C144, Kitt H144, Slade R144, Craig A R144, Deall C144, Sinha Y144, Gabriel J145, Reakes T145, Chervenkoff J145, Strange E145, O'Bryan M145, Murkin C145, Joshi D145, Strange E145, Bergara T145, Naqib S145, Wylam D145, Strange E145, Scotcher S E146, Hewitt C M146, Stoddart M T146, Kerai A146, Trist A J146, Cole S J146, Knight C L146, Stevens S146, Cooper G E146, Ingham R147, Dobson J147, Wylie J147, O'Kane A147, Moradzadeh J147, Duffy A147, Henderson C147, Ashraf S147, McLaughin C147, Hoskins T C148, Reehal R S148, Bookless L R148, McLean R C148, Stone E J148, Wright E V149, Abdikadir H R149, Roberts C149, Spence O149, Srikantharajah M149, Patel M149, Ruiz E M149, Matthews J H149, Gardner E149, Roberts C149, Hester E150, Naran P150, Simpson R150, Minhas M150, Cornish E150, Semnani S A150, Rojoa D150, Radotra A151, Eraifej J151, Eparh K151, Smith D N E151, Mistry B D151, Hickling S L151, Bhangu A151, Din W152, Liu C152, Mithrakumar P152, Mirdavoudi V152, Rashid M153, Mcgenity C153, Hussain O153, Kadicheeni M153, Gardner H153, Anim-Addo N153, Pearce J153, Aslanyan A153, Ntala C153, Sorah T153, Parkin J153, Alizadeh M153, White A154, Edozie F154, Johnston J154, Kahar A154, Navayogaarajah V154, Patel B154, Carter D154, Khonsari P154, Burgess A154, Patel B154, Kong C155, Ponweera A155, Cody A155, Tan Y155, Ng A Y L155, Croall A155, Allan C155, Ng S155, Raghuvir V155, Telfer R156, Greenhalgh A D156, McKerr C N156, Edison M A156, Patel B A156, Dear K156, Hardy M R156, Williams P157, Hassan S157, Sajjad U157, O'Neill E M158, Lopes S158, Healy L158, Jamal N159, Tan S159, Lazenby D159, Husnoo S B159, Beecroft S159, Sarvanandan T159, Weston C160, Bassam N160, Rabinthiran S160, Hayat U160, Ng L160, Varma D160, Sukkari M161, Mian A161, Coates A161, Omar A161, Kim J W161, Coates A161, Sellathurai J161, Mahmood J161, O'Connell C162, Bose R162, Heneghan H162, Lalor P162, Matheson J162, Doherty C162, Cullen C162, Cooper D162, Angelov S162, Drislane C162, Smith A C D163, Kreibich A163, Palkhi E163, Durr A163, Lotfallah A163, Gold D163, Mckean E163, Durr A163, Dhanji A163, Anilkumar A163, Thacoor A163, Durr A163, Siddiqui Z H164, Lim S164, Piquet A164, Anderson S M164, Jindal A164, McCormack D R164, Gulati J164, Ibrahim A164, Jindal A164, Murray S E164, Walsh S L164, McGrath A164, Ziprin P165, Chua E Y165, Lou C N165, Bloomer J165, Paine H R165, Osei-Kuffour D165, White C J165, Szczap A165, Gokani S165, Patel K165, Malys M K166, Reed A166, Torlot G E166, Cumber E M166, Charania A167, Ahmad S167, Varma N167, Cheema H167, Austreng L167, Petra H167, Chaudhary M167, Zegeye M I168, Cheung F168, Coffey D168, Heer R S168, Singh S168, Seager E168, Cumming S168, Suresh R S168, Verma S168, Ptacek I B168, Gwozdz A M168, Yang T169, Khetarpal A A169, Shumon S169, Fung T M P169, Leung W169, Kwang P169, Chew L169, Loke W169, Curran A169, Chan C170, McGarrigle C171, Mohan K171, Cullen S171, Wong E171, Toale C171, Collins D171, Keane N171, Traynor B P171, Shanahan D171, Yan A172, Jafree D J172, Topham C172, Mitrasinovic S172, Omara S172, Gundogan B172, Bingham G172, Lykoudis P M172, Miranda B H172, Whitehurst K173, Kumaran G173, Devabalan Y173, Aziz H173, Shoa M173, Dindyal S173, Yates J A174, Bernstein I174, Rattan G174, Yates J A174, Coulson R175, Stezaker S175, Isaac A175, Salem M175, McBride A175, Isaac A175, McFarlane H175, Yow L175, MacDonald J175, Bartlett R D176, Turaga S176, White U176, Liew W176, Yim N176, Ang A177, Simpson A177, McAuley D177, Craig E177, Murphy L177, Shepherd P177, Kee J Y177, Abdulmajid A177, Chung A177, Warwick H L178, Livesey A178, Holton P178, Theodoreson M D178, Jenkin S L178, Turner J178, Entwisle J H178, Marchal S T178, O'Connor S178, Blege H K178, Aithie J M179, Sabine L M179, Stewart G E179, Jackson S179, Kishore A180, Lankage C M180, Acquaah F180, Joyce H L180, Jindal A181, McKevitt K L181, Coffey C J181, Fawaz A S181, Dolbec K S181, O'Sullivan D A181, Geraghty J M181, Lim E182, Bolton L182, FitzPatrick D182, Robinson C182, Ramtoola T182, Collinson S182, Grundy L183, McEnhill P M183, Harbhajan Singh G S183, Loughran D183, Golding D M183, Keeling R E183, Williams R P183, Whitham R D J183, Yoganathan S183, Nachiappan R183, Egan R J183, Owasil R184, Kwan M L184, He A184, Goh R W184, Bhome R184, Wilson H184, Teoh P J184, Raji K184, Reeves T184, Jayakody N184, Matthams J184, Chong J185, Tan S185, Luk C Y185, Greig R J185, Trail M185, Charalambous G185, Thirumal V185, Rocke A S185, Gardiner N185, Bulley F186, Warren N186, Brennan E186, Fergurson P186, Wilson R186, Whittingham H186, Brown E J187, Khanijau R187, Gandhi K187, Morris S187, Boulton A J187, Chandan N187, Barthorpe A E187, Maamari R187, Sandhu S187, McCann M188, Higgs L188, Balian V188, Reeder C188, Diaper C188, Balian V188, Sale T188, Ali H188, Balian V188, Archer C H189, Clarke A K189, Heskin J189, Hurst P C189, Farmer J D189, O'Flynn L D189, Doan L189, Shuker B A189, Stott G D189, Vithanage N A190, Hoban K A190, Nesargikar P N190, Kennedy H R190, Grossart C M190, Tan E S M190, Roy C S D190, Sim P190, Leslie K E190, Sim D191, Abul M H191, Cody N191, Tay A Y191, Woon E191, Sng S191, Mah J191, Robson J191, Shakweh E192, Wing V C192, Mills H192, Li M M192, Barrow T R192, Balaji S192, Jordan H E M192, Phillips C192, Naveed H192, Hirani S193, Tai A193, Ratnakumaran R193, Sahathevan A193, Shafi A M A193, Seedat M193, Weaver R193, Batho A194, Punj R194, Selvachandran H194, Bhatt N194, Botchey S194, Khonat Z194, Brennan K194, Ong K K195, Morrison C J195, Devlin E195, Linton A195, Galloway E195, McGarvie S195, Ramsay N195, McRobbie H D196, Whewell H196, Dean W196, Nelaj S197, Eragat M197, Mishra A197, Kane T197, Zuhair M197, Wells M197, Wilkinson D197, Woodcock N197, Sun E198, Aziz N198, Abd Ghaffar M K198
Affiliation:
1. overall guarantor 2. University of Bristol, Bristol 3. Hull York Medical School, Hull 4. Leicester Medical School, Leicester 5. University of East Anglia, Norwich 6. University of Nottingham, Nottingham 7. University of Sheffield, Sheffield 8. Queen's University Belfast, Belfast 9. University of Limerick, Limerick 10. National University of Ireland, Galway 11. Royal College of Surgeons in Ireland, Dublin 12. Trinity College, Dublin 13. University College Cork, Cork 14. University College Dublin, Dublin 15. Imperial College, London 16. King's College, London 17. Queen Mary University, London 18. St George's University of London, London 19. University College London, London 20. University of Leeds, Leeds 21. University of Liverpool, Liverpool 22. University of Manchester, Manchester 23. Newcastle University Medical School, Newcastle upon Tyne 24. University of Aberdeen, Aberdeen 25. University of Dundee, Dundee 26. University of Edinburgh, Edinburgh 27. University of Glasgow, Glasgow 28. Brighton and Sussex Medical School, Brighton 29. Peninsula, Exeter and Plymouth 30. SouthamptonMedical School, Southampton 31. University of Cambridge, Cambridge 32. Cardiff University, Cardiff 33. University of Oxford, Oxford 34. Swansea University, Swansea 35. University of Birmingham, Birmingham 36. Keele University, Keele 37. University ofWarwick, Coventry 38. Aberdeen Royal Infirmary, Aberdeen 39. Addenbrooke's Hospital, Cambridge 40. Airedale General Hospital, Steeton 41. Alexandra Hospital, Redditch 42. Antrim Area Hospital, Antrim 43. Arrowe Park Hospital, Wirral 44. Barnet Hospital, Barnet 45. Basingstoke and North Hampshire Hospital, Basingstoke 46. Bedford Hospital, Bedford 47. Belfast City Hospital, Belfast 48. Blackpool Victoria Hospital, Blackpool 49. Bolton Royal Hospital, Bolton 50. Borders General Hospital, Melrose 51. Bradford Royal Infirmary, Bradford 52. Bristol Royal Infirmary, Bristol 53. Charing Cross Hospital, London 54. Chelsea and Westminster Hospital, London 55. Cheltenham General Hospital, Cheltenham 56. Chester Hospital, Chester 57. Colchester Hospital, Colchester 58. Conquest Hospital, Hastings 59. County Hospital, Stafford 60. Craigavon Area Hospital, Craigavon 61. Daisy Hill Hospital, Newry 62. Derriford Hospital, Plymouth 63. Dewsbury Hospital, Dewsbury 64. Diana Princess of Wales Hospital, Grimsby 65. Doncaster Royal Infirmary, Doncaster 66. Dumfries and Galloway Royal Infirmary, Dumfries 67. Ealing Hospital, Southall 68. Eastbourne District General Hospital, Eastbourne 69. East Surrey Hospital, Redhill 70. Epsom Hospital, Epsom 71. Forth Valley Royal Hospital, Larbert 72. Furness General Hospital, Barrow-in-Furness 73. Gartnavel General Hospital, Glasgow 74. George Eliot Hospital, Nuneaton 75. Glangwili General Hospital, Carmarthen 76. Glasgow Royal Infirmary, Glasgow 77. Gloucestershire Royal Hospital, Gloucester 78. Good Hope Hospital, Sutton Coldfield 79. Great WesternHospital, Swindon 80. Hammersmith Hospital, Hammersmith 81. Harrogate District Hospital, Harrogate 82. Heartlands Hospital, Birmingham 83. Hereford County Hospital, Hereford 84. Hillingdon Hospital, Uxbridge 85. Hinchingbrooke Hospital, Huntingdon 86. Homerton University Hospital, London 87. Huddersfield Royal Infirmary, Huddersfield 88. Hull Royal Infirmary, Hull, and Castle Hill Hospital, Cottingham 89. Inverclyde Royal Hospital, Greenock 90. Ipswich Hospital, Ipswich 91. James Connolly Hospital, Dublin 92. James Paget University Hospital, Great Yarmouth 93. Kent and Canterbury Hospital, Canterbury 94. King George Hospital, Ilford 95. King's College Hospital, London 96. King's Mill Hospital, Sutton-in-Ashfield 97. Kingston Hospital, Kingston upon Thames 98. Leicester Royal Infirmary, Leicester 99. Lincoln County Hospital, Lincoln 100. Lister Hospital, Stevenage 101. Manchester Royal Infirmary, Manchester 102. Mater Infirmorum Hospital, Belfast 103. Mayo General Hospital, Castlebar 104. Monklands Hospital, Airdrie 105. Morriston Hospital, Swansea 106. Musgrove Park Hospital, Taunton 107. New Cross Hospital, Wolverhampton 108. Newham University Hospital, London 109. Ninewells Hospital, Dundee 110. Nobles Hospital, Isle of Man 111. Norfolk and Norwich University Hospital, Norwich 112. Northern General Hospital, Sheffield 113. North Manchester General Hospital, Manchester 114. North Middlesex University Hospital NHS Trust, Edmonton 115. North Tyneside General Hospital, North Shields 116. Northwick Park Hospital, Harrow 117. Nottingham City Hospital, Nottingham 118. John Radcliffe and Churchill Hospitals, Oxford 119. Perth Royal Infirmary, Perth 120. Peterborough City Hospital, Peterborough 121. Portsmouth Hospitals NHS Trust Queen Alexandra Hospital, Portsmouth 122. Prince Charles Hospital, Merthyr Tydfil 123. Princess of Wales Hospital, Bridgend 124. Princess Royal Hospital, Haywards Heath 125. Princess Royal University Hospital, Bromley 126. Queen Elizabeth Hospital, Birmingham 127. Queen Elizabeth Hospital, King's Lynn 128. Queen Elizabeth Hospital, Woolwich 129. Queen's Hospital, Romford 130. Queen's Medical Centre, Nottingham 131. Raigmore Hospital, Inverness 132. Rotherham General Hospital, Rotherham 133. Royal Berkshire Hospital, Reading 134. Royal Blackburn Hospital, Blackburn 135. Royal Devon and Exeter Hospital, Exeter 136. Royal Glamorgan Hospital, Ynysmaerdy 137. Royal Gwent Hospital, Newport 138. Royal Infirmary of Edinburgh, Edinburgh 139. Royal Lancaster Infirmary, Lancaster 140. Royal Liverpool Hospital, Liverpool 141. Royal London Hospital, London 142. Royal Preston Hospital, Preston 143. Royal Shrewsbury Hospital, Shrewsbury 144. Royal Stoke University Hospital, Stoke-on-Trent 145. Royal Sussex County Hospital, Brighton 146. Royal United Hospital, Bath 147. Royal Victoria Hospital, Belfast 148. Royal Victoria Infirmary, Newcastle upon Tyne 149. Russell's Hall Hospital, Dudley 150. Salford Royal Hospital, Salford 151. Sandwell General Hospital, West Bromwich 152. Scarborough Hospital, Scarborough 153. Scunthorpe Hospital, Scunthorpe 154. Southend Hospital, Westcliff-on-Sea 155. Southern General Hospital, Glasgow 156. Southmead Hospital, Bristol 157. Southport Hospital, Southport 158. South Tipperary Hospital, Tipperary 159. Stepping Hill Hospital, Stockport 160. St George's Hospital, London 161. St Helier Hospital, Carshalton 162. St James’ Hospital, Dublin 163. St James's University Hospital, Leeds 164. St Luke's Hospital, Limerick 165. St Mary's Hospital, London 166. Stoke Mandeville Hospital, Aylesbury, and High Wycombe Hospital, High Wycombe 167. St Peter's Hospital, Chertsey 168. St Thomas’ Hospital, London 169. Sunderland Royal Hospital, Sunderland 170. Tameside General Hospital, Ashton-under-Lyne 171. The Adelaide and Meath Hospital, Dublin 172. The Royal Free Hospital, London 173. The Whittington Hospital, London 174. Tullamore Hospital, Tullamore 175. Ulster Hospital, Belfast 176. University College London Hospital, London 177. University Hospital Ayr, Ayr 178. University Hospital Coventry and Warwickshire, Coventry 179. University Hospital Crosshouse, Crosshouse 180. University Hospital Lewisham, Lewisham 181. University Hospital Limerick, Limerick 182. University Hospital of South Manchester, Manchester 183. University Hospital of Wales, Cardiff 184. University Hospital Southampton NHS Foundation Trust, Southampton 185. Victoria Hospital, Kirkcaldy 186. Victoria Infirmary, Glasgow 187. Walsall Manor Hospital, Walsall 188. Warrington Hospital, Warrington 189. Warwick Hospital, Warwick 190. Western General Hospital, Edinburgh 191. Western Infirmary, Glasgow 192. West Middlesex Hospital, Isleworth 193. Whipps Cross Hospital, London 194. Whiston Hospital, Prescot 195. Wishaw General Hospital, Wishaw 196. Wrexham Maelor Hospital, Wrexham 197. York Hospital, York 198. Ysbyty Gwynedd, Bangor
Abstract
Abstract
Background
There is currently conflicting evidence surrounding the effects of obesity on postoperative outcomes. Previous studies have found obesity to be associated with adverse events, but others have found no association. The aim of this study was to determine whether increasing body mass index (BMI) is an independent risk factor for development of major postoperative complications.
Methods
This was a multicentre prospective cohort study across the UK and Republic of Ireland. Consecutive patients undergoing elective or emergency gastrointestinal surgery over a 4-month interval (October–December 2014) were eligible for inclusion. The primary outcome was the 30-day major complication rate (Clavien–Dindo grade III–V). BMI was grouped according to the World Health Organization classification. Multilevel logistic regression models were used to adjust for patient, operative and hospital-level effects, creating odds ratios (ORs) and 95 per cent confidence intervals (c.i.).
Results
Of 7965 patients, 2545 (32·0 per cent) were of normal weight, 2673 (33·6 per cent) were overweight and 2747 (34·5 per cent) were obese. Overall, 4925 (61·8 per cent) underwent elective and 3038 (38·1 per cent) emergency operations. The 30-day major complication rate was 11·4 per cent (908 of 7965). In adjusted models, a significant interaction was found between BMI and diagnosis, with an association seen between BMI and major complications for patients with malignancy (overweight: OR 1·59, 95 per cent c.i. 1·12 to 2·29, P = 0·008; obese: OR 1·91, 1·31 to 2·83, P = 0·002; compared with normal weight) but not benign disease (overweight: OR 0·89, 0·71 to 1·12, P = 0·329; obese: OR 0·84, 0·66 to 1·06, P = 0·147).
Conclusion
Overweight and obese patients undergoing surgery for gastrointestinal malignancy are at increased risk of major postoperative complications compared with those of normal weight.
Funder
Academy of Medical Sciences Wellcome Trust
Publisher
Oxford University Press (OUP)
Cited by
68 articles.
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