In vivo bioassay to detect irinotecan-stabilized DNA/topoisomerase I complexes in rats

Author:

Barth Stephan W.,Briviba Karlis,Watzl Bernhard,Jäger Nicole,Marko Doris,Esselen Melanie

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Reference31 articles.

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2. Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins.;Garcia-Carbonero;Clin. Cancer Res.,2002

3. Clinical pharmacokinetics of irinotecan and its metabolites: A population analysis.;Xie;J. Clin. Oncol.,2002

4. Topoisomerase I inhibitors: Camptothecins and beyond.;Pommier;Nat. Rev. Cancer,2006

5. Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1piperidino] carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase.;Satoh;Biol. Pharm. Bull.,1994

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