Two-injection workflow for a liquid chromatography/LTQ-Orbitrap system to completein vivobiotransformation characterization: demonstration with buspirone metabolite identification-Reference-Cited by-同舟云学术

Two-injection workflow for a liquid chromatography/LTQ-Orbitrap system to completein vivobiotransformation characterization: demonstration with buspirone metabolite identification

Published:2009-08-13 Issue:18 Volume:23 Page:3003-3012
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Li Austin C.,Ding Jie,Jiang Xiangyu,Denissen Jon

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/rcm.4207/fullpdf

Reference21 articles.

1. Peer Reviewed: Systematic LC/MS Metabolite Identification in Drug Discovery

2. ‘All-in-One’ analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching

3. Simultaneously quantifying parent drugs and screening for metabolites in plasma pharmacokinetic samples using selected reaction monitoring information-dependent acquisition on a QTrap instrument

4. A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses ofin vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer

5. ‘N-in-one’ strategy for metabolite identification using a liquid chromatography/hybrid triple quadrupole linear ion trap instrument using multiple dependent product ion scans triggered with full mass scan

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