A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses ofin vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer
Author:
Publisher
Wiley
Subject
Spectroscopy
Reference29 articles.
1. In Vitro High Throughput Screening of Compounds for Favorable Metabolic Properties in Drug Discovery.
2. Improvement of “Hit-to-Lead” Optimization by Integration of in Vitro HTS Experimental Models for Early Determination of Pharmacokinetic Properties
3. Optimization of a Higher Throughput Microsomal Stability Screening Assay for Profiling Drug Discovery Candidates
4. Metabolic Stability for Drug Discovery and Development
5. Improving the decision-making process in the structural modification of drug candidates: enhancing metabolic stability
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