Pharmacokinetics of R‐ (−)ondansetron compared with that of S‐ (−)ondansetron in rats using an LC

Pharmacokinetics of R‐ (−)ondansetron compared with that of S‐ (−)ondansetron in rats using an LC–MS/MS method

Published:2018-12-21 Issue:3 Volume:33 Page:e4426
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Duan Mingyu¹²,Zhao Qi¹,Zhong Dafang³,Yuan Yue¹^ORCID

Affiliation:

1. School of Pharmacy, Shenyang Key Laboratory of Functional Drug Carrier MaterialsShenyang Pharmaceutical University Shenyang China

2. Bioanalysis Center, Quarkman Pharmaceutical Technology Co., LTD Benxi Liaoning China

3. State Key Laboratory of Drug Research, Shanghai Institute of Materia MedicaChinese Academy of Sciences Shanghai China

Funder

National Natural Science Foundation of China

Shenyang Science and Technology Bureau

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.4426

Reference22 articles.

1. Clinical pharmacology of ondansetron in postoperative nausea and vomiting;Baber N.;European Journal of Anaesthesiology Supplement,1992

2. Pharmacological properties of GR38032F, a novel antagonist at 5-HT3 receptors

3. Ondansetron: a review of pharmacokinetics and clinical experience in postoperative nausea and vomiting

4. Multiple forms of cytochrome P450 are involved in the metabolism of ondansetron in humans;Dixon C. M.;Drug Metabolism & Disposition the Biological Fate of Chemicals,1995

5. Enantiomeric separation of trimebutinelafutidine and ondansetron by HPLC using chiral stationary phase;Duan M. Y.;Chinese Journal of Pharmaceutical Analysis,2006

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