Synthesis and Biological Characterisation of NovelN-Alkyl-Deoxynojirimycin α-Glucosidase Inhibitors-Reference-Cited by-同舟云学术

Synthesis and Biological Characterisation of NovelN-Alkyl-Deoxynojirimycin α-Glucosidase Inhibitors

Published:2009-04-17 Issue:6 Volume:10 Page:1101-1105
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Rawlings Amy J.,Lomas Hannah,Pilling Adam W.,Lee Marvin J.-R.,Alonzi Dominic S.,Rountree J. S. Shane,Jenkinson Sarah F.,Fleet George W. J.,Dwek Raymond A.,Jones John H.,Butters Terry D.

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Miglustat (NB-DNJ) works as a chaperone for mutated acid β-glucosidase in cells transfected with several Gaucher disease mutations

2. Pharmacotherapeutic strategies using small molecules for the treatment of glycolipid lysosomal storage disorders

3. Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the α-glucosidase inhibitor miglustat

4. α-1-C-Octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease

5. Targeting glycosylation as a therapeutic approach

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