Evidence that Thienamycin Biosynthesis Proceeds via C-5 Epimerization: ThnE Catalyzes the Formation of (2S,5S)-trans-Carboxymethylproline-Reference-Cited by-同舟云学术

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Evidence that Thienamycin Biosynthesis Proceeds via C-5 Epimerization: ThnE Catalyzes the Formation of (2S,5S)-trans-Carboxymethylproline

Published:2009-01-26 Issue:2 Volume:10 Page:246-250
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Hamed Refaat B.,Batchelar Edward T.,Mecinović Jasmin,Claridge Timothy D. W.,Schofield Christopher J.

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbic.200800652/fullpdf

Reference30 articles.

1. The enzymology of clavam and carbapenem biosynthesis

2. Partial purification and characterization of isopenicillin N epimerase activity from Streptomyces clavuligerus

3. Purification and characterization of the isopenicillin N epimerase from Nocardia lactamdurans

4. Purification and properties of isopenicillin N epimerase from Streptomyces clavuligerus

5. Mutational Analysis and Characterization of Nocardicin C-9′ Epimerase

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