Stereoselective Production of Dimethyl-Substituted Carbapenams via Engineered Carbapenem Biosynthesis Enzymes
Author:
Affiliation:
1. Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom
2. Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt
Funder
Medical Research Council
Biotechnology and Biological Sciences Research Council
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acscatal.6b02509
Reference44 articles.
1. Antibiotics in the clinical pipeline in 2013
2. The enzymes of β-lactam biosynthesis
3. Synthetic Carbapenem Antibiotics. I. 1-b-Methylcarbapenem
4. Synthetic carbapenem antibiotics III. 1-Methyl thienamycin
5. Recent Developments in the Field of β-Lactam Antibiotics
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