Catalytic antibodies from HIV-infected patients specifically hydrolyzing viral integrase suppress the enzyme catalytic activities

Author:

Odintsova Elena S.1,Baranova Svetlana V.1,Buneva Valentina N.,Calmels Christina2,Parissi Vincent,Andreola Marie-Line,Zakharova Olga D.1,Nevinsky Georgy A.

Affiliation:

1. Institute of Chemical Biology and Fundamental Medicine; Siberian Division of Russian Academy of Sciences; 8 Lavrentiev Ave.; Novosibirsk; 630090; Russia

2. UMR 5097 CNRS-University Victor Segalen Bordeaux 2; 146 rue Léo Saignat; 33076; Bordeaux cedex; France

Publisher

Wiley

Subject

Molecular Biology,Structural Biology

Reference60 articles.

1. Catalytic heterogeneity of polyclonal RNA-hydrolyzing IgM from sera of patients with lupus erythematosus;Andrievskaya;Med. Sci. Monit.,2000

2. HIV-1 integrase: structural organization, conformational changes, and catalysis;Asante-Appiah;Adv. Virus Res.,1999

3. Small-angle X-ray characterization of the nucleoprotein complexes resulting from DNA-induced oligomerization of HIV-1 integrase;Baranova;Nucleic Acids Res.,2007

4. HIV-1 integrase-hydrolyzing antibodies from sera of HIV-infected patients;Baranova;Biochimie,2009

5. HIV-1 integrase-hydrolyzing IgM antibodies from sera of HIV-infected patients;Baranova;Int. Immunol.,2010

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