Specific anti-integrase abzymes from HIV-infected patients: a comparison of the cleavage sites of intact globular HIV integrase and two 20-mer oligopeptides corresponding to its antigenic determinants

Author:

Odintsova Elena S.1,Dmitrenok Pavel S.2,Buneva Valentina N.,Nevinsky Georgy A.

Affiliation:

1. Institute of Chemical Biology and Fundamental Medicine; Siberian Division of Russian Academy of Sciences; Lavrentiev Ave. 8; Novosibirsk; 630090; Russia

2. Pacific Institute of Bioorganic Chemistry, Far East Division; Russian Academy of Sciences; Vladivostok; 690022; Russia

Publisher

Wiley

Subject

Molecular Biology,Structural Biology

Reference48 articles.

1. HIV-1 integrase: structural organization, conformational changes, and catalysis;Asante-Appiah;Adv. Virus Res.,1999

2. HIV integrase-hydrolyzing antibodies from sera of HIV-infected patients;Baranova;Biochimie,2009

3. HIV-1 integrase-hydrolyzing IgM antibodies from sera of HIV-infected patients;Baranova;Int. Immunol.,2010

4. DNA- and RNA-hydrolyzing antibodies from the blood of patients with various forms of viral hepatitis;Baranovsky;Biochemistry (Mosc.),1997

5. Affinity and catalytic heterogeneity and metal-dependence of polyclonal myelin basic protein-hydrolyzing IgGs from sera of patients with systemic lupus erythematosus;Bezuglova;J. Mol. Recognit.,2011

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