Site‐Directed Mutagenesis of Modular Polyketide Synthase Ketoreductase Domains for Altered Stereochemical Control-Reference-Cited by-同舟云学术

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Site‐Directed Mutagenesis of Modular Polyketide Synthase Ketoreductase Domains for Altered Stereochemical Control

Published:2020-12-22 Issue:7 Volume:22 Page:1122-1150
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Drufva Erin E.¹,Spengler Nolan R.¹,Hix Elijah G.¹,Bailey Constance B.¹^ORCID

Affiliation:

1. Department of Chemistry University of Tennessee, Knoxville Knoxville TN 37996 USA

Funder

University of Tennessee, Knoxville

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.202000613

Reference71 articles.

1. Polyketide biosynthesis: a millennium review

2. Polyketide and Nonribosomal Peptide Antibiotics: Modularity and Versatility

3. Tolerance and Specificity of Polyketide Synthases

4. Structure and Mechanism of the 6-Deoxyerythronolide B Synthase

5. Structure and mechanism of assembly line polyketide synthases

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1. Bioinformatic prediction of the stereoselectivity of modular polyketide synthase: an update of the sequence motifs in ketoreductase domain;Beilstein Journal of Organic Chemistry;2024-07-02

2. Synthesis of Biomimetic Thioesters for Studies of Ketoreductase Domains from the Biosynthesis of Cytotoxic Polyketides;Synlett;2023-11-22

3. Discovery and Biosynthesis of the Cytotoxic Polyene Terpenomycin in Human Pathogenic Nocardia;ACS Chemical Biology;2023-07-27

4. Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition;Nature Communications;2023-02-04

5. Immobilization-stabilization of the dimeric D-amino acid oxidase from porcine kidney;Process Biochemistry;2022-11

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