Hypoxia‐Inducible Factor 1 Alpha–Mediated RelB/APOBEC3B Down‐regulation Allows Hepatitis B Virus Persistence-Reference-Cited by-同舟云学术

Hypoxia‐Inducible Factor 1 Alpha–Mediated RelB/APOBEC3B Down‐regulation Allows Hepatitis B Virus Persistence

Published:2021-08-15 Issue:4 Volume:74 Page:1766-1781
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

Riedl Tobias¹²^ORCID,Faure‐Dupuy Suzanne¹³^ORCID,Rolland Maude⁴^ORCID,Schuehle Svenja¹²,Hizir Zohier⁴,Calderazzo Silvia⁵,Zhuang Xiaodong⁶⁷,Wettengel Jochen⁸,Lopez Martin Alexander⁴,Barnault Romain⁹,Mirakaj Valbona⁹,Prokosch Sandra¹,Heide Danijela¹,Leuchtenberger Corinna¹,Schneider Martin¹⁰,Heßling Bernd¹⁰,Stottmeier Benjamin¹¹¹²,Wessbecher Isabel M.¹¹¹³^ORCID,Schirmacher Peter¹¹¹³,McKeating Jane A⁶⁷,Protzer Ulrike⁸^ORCID,Durantel David¹⁴^ORCID,Lucifora Julie¹⁴^ORCID,Dejardin Emmanuel⁴^ORCID,Heikenwalder Mathias¹³^ORCID

Affiliation:

1. Division of Chronic Inflammation and Cancer German Cancer Research Center (DKFZ) Heidelberg Germany

2. Faculty of Biosciences Heidelberg University Heidelberg Germany

3. Department of Infectious Diseases Molecular Virology Heidelberg University Heidelberg Germany

4. Laboratory of Molecular Immunology and Signal Transduction GIGA‐Institute University of Liège Liège Belgium

5. Division of Biostatistics German Cancer Research Center (DKFZ) Heidelberg Germany

6. Nuffield Department of Medicine University of Oxford Oxford United Kingdom

7. Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI) University of Oxford Oxford United Kingdom

8. Institute of Virology Helmholtz Zentrum München Munich Germany

9. Departement of Anesthesiology and Intensive Care Medicine Molecular Intensive Care Medicine University Hospital TübingenEberhard‐Karls‐University Tuebingen Germany

10. Mass Spectrometry Based Protein Analysis Unit German Cancer Research Center (DKFZ) Heidelberg Germany

11. Institute of Pathology University Hospital Heidelberg Heidelberg Germany

12. German Center for Infection Research (DZIF)partner site Heidelberg Heidelberg Germany

13. Tissue Bank of the German Center for Infection Research (DZIF) Institute of Pathology Heidelberg University Hospital Heidelberg Germany

14. INSERM U1052 Cancer Research Center of Lyon (CRCL) University of Lyon (UCBL1)CNRS UMR_5286, Centre Léon Bérard (CLB) Lyon France

Funder

Deutsche Krebshilfe

German Cancer Research Center

Fonds De La Recherche Scientifique - FNRS

Institut National de la Santé et de la Recherche Médicale

H2020 European Research Council

Chinese Academy of Medical Sciences

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Hepatology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep.31902

Reference28 articles.

1. https://www.who.int/news‐room/fact‐sheets/detail/hepatitis‐b. Accessed August 2021.

2. Therapeutic strategies for hepatitis B virus infection: towards a cure

3. Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes

4. Recent advances in the discovery and development of TLR ligands as novel therapeutics for chronic HBV and HIV infections

5. Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism

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