Allostery mediates ligand binding to WWOX tumor suppressor via a conformational switch-Reference-Cited by-同舟云学术

Allostery mediates ligand binding to WWOX tumor suppressor via a conformational switch

Published:2015-02-19 Issue:4 Volume:28 Page:220-231
ISSN:0952-3499
Container-title:Journal of Molecular Recognition
language:en
Short-container-title:J. Mol. Recognit.

Author:

Schuchardt Brett J.¹,Mikles David C.¹,Bhat Vikas¹,McDonald Caleb B.¹,Sudol Marius²³,Farooq Amjad¹^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology; Leonard Miller School of Medicine University of Miami; Miami FL 33136 USA

2. Weis Center for Research; Geisinger Clinic; Danville PA 17822 USA

3. Department of Medicine; Mount Sinai School of Medicine; New York NY 10029 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Molecular Biology,Structural Biology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jmr.2419/fullpdf

Reference61 articles.

1. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer;Bednarek;Cancer Res,2000

2. WWOX, the FRA16D gene, behaves as a suppressor of tumor growth;Bednarek;Cancer Res,2001

3. WWOX, a new potential tumor suppressor gene;Hezova;Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub,2007

4. Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status;Nunez;Breast Cancer Res Treat,2005

5. Loss of WWOX expression in gastric carcinoma;Aqeilan;Clin Cancer Res,2004

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structural insights into the role of the WW2 domain on tandem WW–PPxY motif interactions of oxidoreductase WWOX;Journal of Biological Chemistry;2022-08

2. WWOX Controls Cell Survival, Immune Response and Disease Progression by pY33 to pS14 Transition to Alternate Signaling Partners;Cells;2022-07-07

3. WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles;Journal of Virology;2022-03-23

4. Tandem WW/PPxY motif interactions in WWOX: the multifaceted role of the second WW domain;2021-12-01

5. WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 VLPs;2021-11-20