Modeling G protein-coupled receptors for structure-based drug discovery using low-frequency normal modes for refinement of homology models: Application to H3 antagonists
Author:
Publisher
Wiley
Subject
Molecular Biology,Biochemistry,Structural Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.22571/fullpdf
Reference79 articles.
1. Uncovering molecular mechanisms involved in activation of G protein-coupled receptors;Gether;Endocr Rev,2000
2. Molecular mechanism of 7tm receptor activation-a global toggle switch model;Schwartz;Annu Rev Pharmacol Toxicol,2006
3. Structural basis for activation of G protein-coupled receptors;Gether;Pharmacol Toxicol,2002
4. Drug discovery: a historical perspective;Drews;Science,2000
5. The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure;Okada;J Mol Biol,2004
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