Development and Qualification of Physiologically Based Pharmacokinetic Models for Drugs With Atypical Distribution Behavior: A Desipramine Case Study
Author:
Affiliation:
1. Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy; University of Florida; Lake Nona (Orlando) Florida USA
2. Simulations Plus, Inc.; Lancaster California USA
Publisher
Wiley
Subject
Pharmacology (medical),Modeling and Simulation
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4. Desipramine and 2-hydroxy-desipramine pharmacokinetics in normal volunteers;DeVane;Eur. Clin. Pharmacol.,1981
5. Treatment of childhood hyperactivity with desipramine: plasma drug concentration, cardiovascular effects, plasma and urinary catecholamine levels, and clinical response;Donnelly;Clin. Pharmacol. Ther.,1986
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