Constitutive Triglyceride Turnover into the Mesenteric Lymph Is Unable to Support Efficient Lymphatic Transport of a Biomimetic Triglyceride Prodrug-Reference-Cited by-同舟云学术

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Constitutive Triglyceride Turnover into the Mesenteric Lymph Is Unable to Support Efficient Lymphatic Transport of a Biomimetic Triglyceride Prodrug

Published:2016-02 Issue:2 Volume:105 Page:786-796
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Han Sifei,Hu Luojuan,Quach Tim,Simpson Jamie S.,Trevaskis Natalie L.,Porter Christopher J.H.

Funder

National Health and Medical Research Council

Australian Research Council of Australia

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference45 articles.

1. Intestinal lymphatic drug transport: An update;Porter;Adv Drug Deliv Rev,2001

2. An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat;Trevaskis;Drug Metab Dispos,2006

3. The role of lymphatic transport on the systemic bioavailability of the Bcl-2 protein family inhibitors Navitoclax (ABT-263) and ABT-199;Choo;Drug Metab Dispos,2014

4. The physiology of the lymphatic system;Swartz;Adv Drug Deliv Rev,2001

5. Engineering approaches to immunotherapy;Swartz;Sci Transl Med,2012

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2. Prodrug Rewards in Medicinal Chemistry: An Advance and Challenges Approach for Drug Designing;Chemistry & Biodiversity;2023-11

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4. Increasing Linker Chain Length and Intestinal Stability Enhances Lymphatic Transport and Lymph Node Exposure of Triglyceride Mimetic Prodrugs of a Model Immunomodulator Mycophenolic Acid;Molecular Pharmaceutics;2023-03-30

5. Long chain triglyceride-lipid formulation promotes the oral absorption of the lipidic prodrugs through coincident intestinal behaviors;European Journal of Pharmaceutics and Biopharmaceutics;2022-07

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