Synthesis of cyclosporine. Total syntheses of ?cyclosporin A? and ?cyclosporin H?, two fungal metabolites isolated from the speciesTolypocladium inflatum GAMS-Reference-Cited by-同舟云学术

Synthesis of cyclosporine. Total syntheses of ?cyclosporin A? and ?cyclosporin H?, two fungal metabolites isolated from the speciesTolypocladium inflatum GAMS

Published:1984-03-14 Issue:2 Volume:67 Page:502-525
ISSN:0018-019X
Container-title:Helvetica Chimica Acta
language:de
Short-container-title:Helv. Chim. Acta

Author:

Wenger Roland M.

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis

Reference40 articles.

1. Synthesis of Cyclosporine. I. Synthesis of enantiomerically pure (2S,3R,4R,6E)-3-hydroxy -4-methyl-2-methylamino-6-octenoic acid starting from tartaric acid

2. Synthesis of Cyclosporine. Part II. Synthesis of Boc-D-Ala-MeLeu-MeLeu-MeVal-OH, a part of the peptide sequence of cyclosporine, by different strategic ways and synthesis of its isomers Boc-D-Ala-MeLeu-D-MeLeu-MeVal-OH, Boc-D-MeLeu-DMeVal-OH, and Boc-D-Ala-MeLeu-MeLeu-D-MeVal-OH as reference compounds

3. ?Chemistry of Cyclosporine?, in ?Cyclosporin A?, ed. Elsevier Biomed., Amsterdam, 1982, p. 19.

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