A novel approach to amino acid synthesis: acid-assisted reactions with dimethyl carbonate for efficient O-methylated, N,O-methylated and N-formylated derivatives

Author:

Worsawat Pattamabhorn1,Noppawan Pakin2ORCID,Supanchaiyamat Nontipa1ORCID,Wu Himmy3,McElroy Con R.34ORCID,Hunt Andrew J.1ORCID

Affiliation:

1. Materials Chemistry Research Center (MCRC), Department of Chemistry and Centre of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand

2. Department of Chemistry, Faculty of Science, Mahasarakham University, Maha Sarakham, 44150, Thailand

3. Department of Chemistry, University of York, York, YO10 5DD, UK

4. School of Chemistry, University of Lincoln, Brayford Pool Campus, Lincoln, LN6 7TS, UK

Abstract

A novel and efficient method has been developed for the modification of amino acids using a dimethyl carbonate (DMC) in an acidic system.

Funder

National Research Council of Thailand

Materials Chemistry Research Center, Khon Kaen University

Publisher

Royal Society of Chemistry (RSC)

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