Cell‐Based Micro/Nano‐Robots for Biomedical Applications: A Review

Author:

Chen Bo1,Sun Hongyan1,Zhang Jiaying1,Xu Junjie1,Song Zeyu1,Zhan Guangdong1,Bai Xue2,Feng Lin13ORCID

Affiliation:

1. School of Mechanical Engineering and Automation Beihang University Beijing 100191 China

2. School of Biomedical Engineering Capital Medical University Beijing 100069 China

3. Beijing Advanced Innovation Center for Biomedical Engineering Beihang University Beijing 100191 China

Abstract

AbstractMicro/nano‐robots are powerful tools for biomedical applications and are applied in disease diagnosis, tumor imaging, drug delivery, and targeted therapy. Among the various types of micro‐robots, cell‐based micro‐robots exhibit unique properties because of their different cell sources. In combination with various actuation methods, particularly externally propelled methods, cell‐based microrobots have enormous potential for biomedical applications. This review introduces recent progress and applications of cell‐based micro/nano‐robots. Different actuation methods for micro/nano‐robots are summarized, and cell‐based micro‐robots with different cell templates are introduced. Furthermore, the review focuses on the combination of cell‐based micro/nano‐robots with precise control using different external fields. Potential challenges, further prospects, and clinical translations are also discussed.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Wiley

Subject

Biomaterials,Biotechnology,General Materials Science,General Chemistry

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